Can't pick up items

[Orchids_Mantis]

Not sure if this belongs in bugs or troubleshooting, but either way this is getting aggravating. I can buy and sell stuff, and pick up sap and spoiled mushrooms, but anything else I am either unable to obtain, or just vanishes -including quest items like lost souls and pickaxes. I can see them on the ground, I highlight them with my cursor and the name appears, and when I click on them they disappear, but they are not in my inventory; they just vanish (and for some odd reason, if my party members pick them up, they don't show on my quest list -ordinarilly, 2 members can share items like that, can't they?).

[Jhanniss]

Quest items generally are no-drop and no-transfer so if another person got them in your group, they alone get points for it if they too are questing that item.

[Tamlinari]

It does sound like your character may be bugged.
Just my opinion.
:D

[Trebori]

Are you in a party and the loot is set to sequential?

It sounds like it. If you are than someone else in the group is getting the items.

The items go to the next person in line in sequential regardless of who picks it up or if it is a quest item they can't use.